Nathan Seifert, Ph.D.
Chemistry and Chemical & Biomedical Engineering Department
Tagliatela College of Engineering
Education
Ph.D., Physical Chemistry, University of Virginia
B.A., Chemistry, Amherst College
About Nathan
Nathan Seifert joined the faculty of the University of New Haven in August 2021. His research interests since graduate school have focused on the development of chirped pulse Fourier transform microwave (CP-FTMW) spectroscopic techniques, and applications of CP-FTMW spectroscopy for both physical chemistry and analytical applications. Though much of his previous research has been on the experimental aspects of molecular spectroscopy, Nathan has a strong interest in applying data science and machine learning techniques for the automated interpretation of molecular spectra in analytical chemistry and structure determination.
Nathan鈥檚 research at the University of New Haven going forward will center on development of a low-cost CP-FTMW spectrometer for structure determination and chemical mixture analysis, and the development of software and machine learning techniques for digital signal processing, spectral assignment, structure elucidation, and novel improvements to the software-hardware instrument interface.
Selected Publications
D. P. Zaleski, R. Sivaramakrishnan, H. R. Weller, N. A. Seifert, D. H. Bross, B. Ruscic, K. B. Moore III, S. N. Elliott, A. V. Copan, L. B. Harding, S. J. Klippenstein, R. W. Field, K. Prozument, 鈥淪ubstitution Reactions in the Pyrolysis of Acetone Revealed through a Modeling, Experiment, Theory Paradigm,鈥 J. Am. Chem. Soc. 2021, 143, 3124-3142.
F. Xie, N. A. Seifert, W. J盲ger, Y. Xu, 鈥淐onformational Panorama and Chirality Controlled Structure鈥揈nergy Relationship in a Chiral Carboxylic Acid Dimer,鈥 Angew. Chem. Int. Ed. 2020, 59, 15703-15710.
3) N. A. Seifert, A. S. Hazrah, W. J盲ger, 鈥淭he 1-Naphthol Dimer and Its Surprising Preference for 蟺鈥撓 Stacking over Hydrogen Bonding,鈥 J. Phys. Chem. Lett. 2019, 10, 2836-2841.
S. Oswald, N. A. Seifert, F. Bohle, M. Gawrilow, S. Grimme, W. J盲ger, Y. Xu, M. A. Suhm, 鈥淭he Chiral Trimer and a Metastable Chiral Dimer of Achiral Hexafluoroisopropanol: A Multi鈥怣essenger Study,鈥 Angew. Chem. Int. Ed. 2019, 131, 5134
N. A. Seifert, J. Thomas, W. J盲ger, Y. Xu, 鈥淩otational spectra and theoretical study of tetramers and trimers of 2-fluoroethanol: dramatic intermolecular compensation for intramolecular instability,鈥 Phys. Chem. Chem. Phys. 2018, 20, 27630-27637.
J. Thomas, N. A. Seifert, W. J盲ger, Y. Xu, 鈥淎 Direct Link from the Gas to the Condensed Phase: A Rotational Spectroscopic Study of 2, 2, 2鈥怲rifluoroethanol Trimers,鈥 Angew. Chem. Int. Ed. 2017, 129, 6386-6390.
N. A. Seifert, I. A. Finneran, C. P茅rez, D. P. Zaleski, J. L. Neill, A. L. Steber, R. D. Suenram, A. Lesarri, S. T. Shipman, B. H. Pate, 鈥淎UTOFIT, an automated fitting tool for broadband rotational spectra, and applications to 1-hexanal,鈥 J. Mol. Spectrosc. 2015, 312, 13-21.
C. P茅rez, D. P. Zaleski, N. A. Seifert, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, 鈥淗ydrogen Bond Cooperativity and the Three鈥怐imensional Structures of Water Nonamers and Decamers,鈥 Angew. Chem. Int. Ed. 2014, 126, 14596-14600
C. P茅rez, S. Lobsiger, N. A. Seifert, D. P. Zaleski, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, 鈥淏roadband Fourier transform rotational spectroscopy for structure determination: The water heptamer,鈥 Chem. Phys. Lett. 2013, 571, 1-15.
C. P茅rez, M. T. Muckle, D. P. Zaleski, N. A. Seifert, B. Temelso, G. C. Shields, Z. Kisiel, B. H. Pate, 鈥淪tructures of cage, prism, and book isomers of water hexamer from broadband rotational spectroscopy,鈥 Science 2012, 336, 897-901.
Full publication list can be found at